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Alpena is a city in the U.S. state of Michigan, as well as the county seat of Alpena County. Its population at the 2010 census was 10,483. This number increases during summer due to a large number of visitors.

The Thunder Bay National Marine Sanctuary is located in the city. This and Traverse City are considered to be the anchor cities of Northern Michigan.

The largest employer in the city is the Alpena Regional Medical Center, a federally designated rural regional medical referral center. Tourism is an important contributor to the local economy. Alpena has an industrial base as well. The city has the LaFarge Company's cement plant and to Besser Block Co. (maker of a concrete block making machinery), as well as a drywall board manufacturing facility owned by Decorative Panels International.

It has one local daily and a number of radio stations, along with one local television station. It has a number of local activities and festivals, as well as museums and a public library.

The population predominantly comprises White Americans.