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Louisville, is the largest city in Kentucky. It is located at the Falls of the Ohio, at the Kentucky-Indiana border.

In 1778, Lt. Col. George Rogers Clark and his troops established Fort Nelson within the current boundaries of Louisville in 1778. The following year, the town was named after France's King Louis XVI, who supported the colonists in the Revolutionary War. Its location at the Ohio River's falls gave the city both military and economic importance. It had become a major river port. The completion of the Portland Canal around the falls in 1830 further generated its economic growth and cultural development.

The city is popularly  known for horse racing . It is a leading producer of gin, whiskey, tobacco, and baseball bats. Other major exports include chemicals, rubber, paint, and electrical appliances. It is home to the American Printing House for the Blind, the world's largest publisher of books in Braille. The Kentucky School Blind. The University of Louisville was the first city-owned university in the U.S., founded in  and the Louisville Free Public Library was one of the first public systems in the country.