Gaylesville is a town in Cherokee County, Alabama. It has a total land area of 0.35 square miles.
Production, transportation and material moving are the major economic activities here. Other activities include professional services, management and financial operations, and to a minor extent farming, forestry and related activities. Gaylesville High School is the local public school. The closest hospital is Cherokee Medical Center, located 10 miles away in Centre. The cost of living here is 14.10% lower than the country average, making living here comparatively cheaper.
The town gets 56 inches of rain annually. The number of days in a year with measurable precipitation is 104. Snowfall is about 2 inches annually.