The town of Mathiston is located within the counties of Choctaw and Webster. It covers a total area of 6.4 sq. km. Businesses related to auto repair and service, freight forwarding, supplies of fruits and vegetables, contracting in paving, consultancy in real estate and contracting in remodeling and repairing, enhance the financial viability of the city. Commercial spaces are utilized by clinics, garden centers, restaurants, tourist information centers and road side services.