Niota is an unincorporated village in Appanoose Township located in the U.S. state of Illinois. It is within Hancock County on Mississippi River and the eastern end of the Fort Madison Toll Bridge. It coordinates at 40°37′03″N 91°17′17″W. The elevation is 522 feet above sea level. Niota is served by Illinois Route 96 which is included in the Great River Road. It has Zip code 62358.