Pettigrew is an unincorporated village located in the U.S. state of Arkansas. It is within Madison County on Arkansas Highway 16 6.5 miles of St. Paul to the east and 3 miles in southwest Boston. It coordinates at 35°49′04″N 93°38′55″W. The elevation is 1,831 feet above sea level. Pettigrew has a post office with Zip code 72752.