Samantha is an unincorporated community in Alabama, United States. It is within Tuscaloosa County lies across U.S. Route 43 about 14.8 miles north of Tuscaloosa. Samantha total population was about 4,347 (51.0 percent Males and 49.0 percent Females) at 2007 census data. It was named by the wife of the first postmaster Sylvester Monroe Cowden. Samantha has a post office with Zip code 35482. Both Major League Baseball pitcher and player Dan Boone and Ike Boone are Samantha's home pride. In 2015, the median household income was $56,104. Samantha estimated per capita income was $23,652. Elevation is 394 feet at 33°25′20″N 87°36′19″W.