St. Joe is a town located in the U.S. state of Arkansas. It is within Searcy County with a total area of 1.25 square miles at 36°1′44″N 92°48′44″W. The elevation is 797 feet above sea level. As of the 2010 census data, it had a total population of 132. The population density was 101.84/sq mi. Estimated per capita income in 2016 was $18,290. It has Zip code 72675.